CASP3 antibody - C-terminal region
Produktgrößen
25ul
£177,00
ARP58987-P050-25UL
100 ul
£412,00
ARP58987-P050-100UL
Über dieses Produkt
- SKU:
- ARP58987-P050
- Zusätzliche Namen:
- CPP32; SCA-1; CPP32B
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- CASP3 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits; large and small; that dimerize to form the active enzyme. This protein cleaves and activates caspases 6; 7 and 9; and the protein itself is processed by caspases 8; 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein; which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
- Gendetails:
- Caspase 3; apoptosis-related cysteine peptidase
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C terminal region of human CASP3
- Molekulargewicht:
- 12kDa
- Proteindetails:
- Caspase-3
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php