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Antikörper

DAZ1 antibody - N-terminal region

Produktgrößen
25ul
£177,00
ARP58711-P050-25UL
100 ul
£412,00
ARP58711-P050-100UL
Über dieses Produkt
SKU:
ARP58711-P050
Zusätzliche Namen:
DAZ; SPGY
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
DAZ1 is a RNA-binding protein that plays an essential role in spermatogenesis. DAZ1 may act by binding to the 3'-UTR of mRNAs and regulating their translation.This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells; particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon; called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains three copies of the 10.8 kb repeat. However; no transcripts containing three copies of the RRM domain have been described; thus the RefSeq for this gene contains only two RRM domains. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gendetails:
Deleted in azoospermia 1
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human DAZ1
Molekulargewicht:
64kDa
Proteindetails:
Deleted in azoospermia protein 1
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody