FBXW4 Antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP57577-P050-25UL
100 ul
£412,00
ARP57577-P050-100UL
Über dieses Produkt
- SKU:
- ARP57577-P050
- Zusätzliche Namen:
- DAC; FBW4; FBWD4; SHFM3; SHSF3
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene is a member of the F-box/WD-40 gene family; which recruit specific target proteins through their WD-40 protein-protein binding domains for ubiquitin mediated degradation. In mouse; a highly similar protein is thought to be responsible for maintaining the apical ectodermal ridge of developing limb buds; disruption of the mouse gene results in the absence of central digits; underdeveloped or absent metacarpal/metatarsal bones and syndactyly. This phenotype is remarkably similar to split hand-split foot malformation in humans; a clinically heterogeneous condition with a variety of modes of transmission. An autosomal recessive form has been mapped to the chromosomal region where this gene is located; and complex rearrangements involving duplications of this gene and others have been associated with the condition. A pseudogene of this locus has been mapped to one of the introns of the BCR gene on chromosome 22.
- Gendetails:
- F-box and WD repeat domain containing 4
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N-terminal region of human FBXW4
- Molekulargewicht:
- 35kDa
- Proteindetails:
- F-box/WD repeat-containing protein 4
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php