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Antikörper

BLMH antibody - middle region

Produktgrößen
25ul
£177,00
ARP56106-P050-25UL
100 ul
£412,00
ARP56106-P050-100UL
Über dieses Produkt
SKU:
ARP56106-P050
Zusätzliche Namen:
BH; BMH
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
The normal physiological role of BLM hydrolase is unknown; but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity.Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however; the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM); an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gendetails:
Bleomycin hydrolase
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human BLMH
Molekulargewicht:
52kDa
Proteindetails:
Bleomycin hydrolase
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody