Chmp2b Antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP54967-P050-25UL
100 ul
£412,00
ARP54967-P050-100UL
Über dieses Produkt
- SKU:
- ARP54967-P050
- Zusätzliche Namen:
- RGD1306781
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Chmp2b is involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Chmp2b recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly; possibly in combination with membrane fission. Chmp2b redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins; such as stimulated growth factor receptors; lysosomal enzymes and lipids. In conjunction with the ESCRT machinery Chmp2b also appears to function in topologically equivalent membrane fission events; such as the terminal stages of cytokinesis. Involved in cytokinesis .
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Chmp2b
- Molekulargewicht:
- 23kDa
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php