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Antikörper

ETF1 antibody - N-terminal region

Produktgrößen
25ul
£177,00
ARP54738-P050-25UL
100 ul
£412,00
ARP54738-P050-100UL
Über dieses Produkt
SKU:
ARP54738-P050
Zusätzliche Namen:
ERF; RF1; ERF1; TB3-1; D5S1995; SUP45L1
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
Termination of protein biosynthesis and release of the nascent polypeptide chain are signaled by the presence of an in-frame stop codon at the aminoacyl site of the ribosome. The process of translation termination is universal and is mediated by protein release factors (RFs) and GTP. A class 1 RF recognizes the stop codon and promotes the hydrolysis of the ester bond linking the polypeptide chain with the peptidyl site tRNA; a reaction catalyzed at the peptidyl transferase center of the ribosome. Class 2 RFs; which are not codon specific and do not recognize codons; stimulate class 1 RF activity and confer GTP dependency upon the process. In prokaryotes; both class 1 RFs; RF1 and RF2; recognize UAA; however; UAG and UGA are decoded specifically by RF1 and RF2; respectively. In eukaryotes; eRF1; or ETF1; the functional counterpart of RF1 and RF2; functions as an omnipotent RF; decoding all 3 stop codons (Frolova et al.; 1994 [PubMed 7990965]).
Gendetails:
Eukaryotic translation termination factor 1
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human ETF1
Molekulargewicht:
49kDa
Proteindetails:
Eukaryotic peptide chain release factor subunit 1
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody