GRN Antibody - middle region
Produktgrößen
25ul
£177,00
ARP54642-P050-25UL
100 ul
£412,00
ARP54642-P050-100UL
Über dieses Produkt
- SKU:
- ARP54642-P050
- Zusätzliche Namen:
- GEP; GP88; PEPI; PGRN; CLN11; PCDGF
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Granulins are a family of secreted; glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein; progranulin; is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active; 6 kDa peptides. These smaller cleavage products are named granulin A; granulin B; granulin C; etc. Epithelins 1 and 2 are synonymous with granulins A and B; respectively. Both the peptides and intact granulin protein regulate cell growth. However; different members of the granulin protein family may act as inhibitors; stimulators; or have dual actions on cell growth. Granulin family members are important in normal development; wound healing; and tumorigenesis.
- Gendetails:
- granulin
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of Human GRN
- Molekulargewicht:
- 64 kDa
- Proteindetails:
- Granulins
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php