GNAI1 antibody - middle region
Produktgrößen
25ul
£177,00
ARP54630-P050-25UL
100 ul
£412,00
ARP54630-P050-100UL
Über dieses Produkt
- SKU:
- ARP54630-P050
- Zusätzliche Namen:
- Gi
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Guanine nucleotide-binding proteins (G proteins) form a large family of signal-transducing molecules. They are found as heterotrimers made up of alpha; beta; and gamma subunits. Members of the G protein family have been characterized most extensively on the basis of the alpha subunit; which binds guanine nucleotide; is capable of hydrolyzing GTP; and interacts with specific receptor and effector molecules. The G protein family includes Gs and Gi; the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; Go; a protein abundant in brain (GNAO1); and transducin-1 (GNAT1) and transducin-2 (GNAT2); proteins involved in phototransduction in retinal rods and cones; respectively.Guanine nucleotide-binding proteins (G proteins) form a large family of signal-transducing molecules. They are found as heterotrimers made up of alpha; beta; and gamma subunits. Members of the G protein family have been characterized most extensively on the basis of the alpha subunit; which binds guanine nucleotide; is capable of hydrolyzing GTP; and interacts with specific receptor and effector molecules. The G protein family includes Gs (MIM 139320) and Gi; the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; Go; a protein abundant in brain (GNAO1; MIM 139311); and transducin-1 (GNAT1; MIM 139330) and transducin-2 (GNAT2; MIM 139340); proteins involved in phototransduction in retinal rods and cones; respectively (Sullivan et al.; 1986 [PubMed 3092218]; Bray et al.; 1987 [PubMed 3110783]). Suki et al. (1987) [PubMed 2440724] concluded that the human genome contains at least 3 nonallelic genes for alpha-i-type subunits of G protein; see; e.g; GNAI2 (MIM 139360); GNAI3 (MIM 139370); and GNAIH (MIM 139180).[supplied by OMIM]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
- Gendetails:
- Guanine nucleotide binding protein (G protein); alpha inhibiting activity polypeptide 1
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human GNAI1
- Molekulargewicht:
- 40kDa
- Proteindetails:
- Guanine nucleotide-binding protein G(i) subunit alpha-1
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php