GALE antibody - middle region
Produktgrößen
25ul
£177,00
ARP54394-P050-25UL
100 ul
£412,00
ARP54394-P050-100UL
Über dieses Produkt
- SKU:
- ARP54394-P050
- Zusätzliche Namen:
- SDR1E1
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- GALE is an UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose; and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose; but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia; also referred to as galactosemia type 3; a disease characterized by liver damage; early-onset cataracts; deafness and mental retardation; with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form).
- Gendetails:
- UDP-galactose-4-epimerase
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human GALE
- Molekulargewicht:
- 38kDa
- Proteindetails:
- UDP-glucose 4-epimerase
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php