ERCC5 Antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP54288-P050-25UL
100 ul
£412,00
ARP54288-P050-100UL
Über dieses Produkt
- SKU:
- ARP54288-P050
- Zusätzliche Namen:
- XPG; UVDR; XPGC; COFS3; ERCM2; ERCC5-201
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes; including RNA polymerase II transcription; and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G); which is also referred to as xeroderma pigmentosum VII (XP7); a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome; which is characterized by severe growth defects; mental retardation; and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic; immunoglobulin-like variable motif containing) gene.
- Gendetails:
- excision repair cross-complementing rodent repair deficiency; complementation group 5
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human ERCC5
- Molekulargewicht:
- 133 kDa
- Proteindetails:
- DNA repair protein complementing XP-G cells
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php