Cish antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP52798-P050-25UL
100 ul
£412,00
ARP52798-P050-100UL
Über dieses Produkt
- SKU:
- ARP52798-P050
- Zusätzliche Namen:
- C; CI; Cis; F17; F23; CIS1; SOCS; CIS-1
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin; prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
- Gendetails:
- Cytokine inducible SH2-containing protein
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Molekulargewicht:
- 28kDa
- Proteindetails:
- Cytokine-inducible SH2-containing protein
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php