CAPN10 antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP52404-P050-25UL
100 ul
£412,00
ARP52404-P050-100UL
Über dieses Produkt
- SKU:
- ARP52404-P050
- Zusätzliche Namen:
- CANP10; NIDDM1
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- CAPN10 is the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.Calpains are ubiquitous; well-conserved family of calcium-dependent; cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I; the N-terminal regulatory domain that is processed upon calpain activation; domain II; the protease domain; domain III; a linker domain of unknown function; and domain IV; the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM) and located within the NIDDM1 region. Multiple alternative transcript variants encoding different isoforms have been described for this gene.
- Gendetails:
- Calpain 10
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human CAPN10
- Molekulargewicht:
- 58kDa
- Proteindetails:
- Calpain-10
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php