EGLN3 antibody - C-terminal region
Produktgrößen
25ul
£177,00
ARP52402-P050-25UL
100 ul
£412,00
ARP52402-P050-100UL
Über dieses Produkt
- SKU:
- ARP52402-P050
- Zusätzliche Namen:
- PHD3; HIFPH3; HIFP4H3
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- EGLN3 catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. It hydroxylates HIF-1 alpha at 'Pro-564'; and HIF-2 alpha. EGLN3 functions as a cellular oxygen sensor and; under normoxic conditions; targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. It may play a role in cell growth regulation in muscle cells and in apoptosis in neuronal tissue. EGLN3 promotes cell death through a caspase-dependent mechanism.
- Gendetails:
- Egl nine homolog 3 (C. elegans)
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C terminal region of human EGLN3
- Molekulargewicht:
- 27kDa
- Proteindetails:
- Egl nine homolog 3
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php