CSNK1E antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP51987-P050-25UL
100 ul
£412,00
ARP51987-P050-100UL
Über dieses Produkt
- SKU:
- ARP51987-P050
- Zusätzliche Namen:
- CKIe; HCKIE; CKIepsilon
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. CSNK1E can phosphorylate a large number of proteins. CSNK1E participates in Wnt signaling and is the central component of the circadian clock. It may act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. CSNK1E inhibits cytokine-induced granuloytic differentiation.The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family; whose members have been implicated in the control of cytoplasmic and nuclear processes; including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins; including itself. This protein has been shown to phosphorylate period; a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene.
- Gendetails:
- Casein kinase 1; epsilon
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human CSNK1E
- Molekulargewicht:
- 47kDa
- Proteindetails:
- Casein kinase I isoform epsilon
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php