GP1BA antibody - C-terminal region
Produktgrößen
25ul
£177,00
ARP51319-P050-25UL
100 ul
£412,00
ARP51319-P050-100UL
Über dieses Produkt
- SKU:
- ARP51319-P050
- Zusätzliche Namen:
- BSS; GP1B; VWDP; CD42B; GPIbA; BDPLT1; BDPLT3; DBPLT3; GPIbalpha; CD42b-alpha
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer; an alpha chain and a beta chain; that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury; and also initiates signaling events within the platelet that lead to enhanced platelet activation; thrombosis; and hemostasis. GP1BA is the alpha subunit.Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer; an alpha chain and a beta chain; that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury; and also initiates signaling events within the platelet that lead to enhanced platelet activation; thrombosis; and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene; some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
- Gendetails:
- Glycoprotein Ib (platelet); alpha polypeptide
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C terminal region of human GP1BA
- Molekulargewicht:
- 72 kDa
- Proteindetails:
- Platelet glycoprotein Ib alpha EMBL BAJ15421.1
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php