ANTXR1 antibody - middle region
Produktgrößen
25ul
£177,00
ARP50040-P050-25UL
100 ul
£412,00
ARP50040-P050-100UL
Über dieses Produkt
- SKU:
- ARP50040-P050
- Zusätzliche Namen:
- ATR; GAPO; TEM8
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. ANTXR1 has been shown to also be a docking protein or receptor for Bacillus anthracis toxin; the causative agent of the disease; anthrax. The binding of the protective antigen (PA) component; of the tripartite anthrax toxin; to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell; the other two components of anthrax toxin; edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.The protein encoded by this gene is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin; the causative agent of the disease; anthrax. The binding of the protective antigen (PA) component; of the tripartite anthrax toxin; to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell; the other two components of anthrax toxin; edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants have been described.
- Gendetails:
- Anthrax toxin receptor 1
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human ANTXR1
- Molekulargewicht:
- 60kDa
- Proteindetails:
- Anthrax toxin receptor 1
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php