GNPTAB antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP49815-P050-25UL
100 ul
£412,00
ARP49815-P050-100UL
Über dieses Produkt
- SKU:
- ARP49815-P050
- Zusätzliche Namen:
- ICD; GNPTA
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase; a heterohexameric complex composed of two alpha; two beta; and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus; the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.
- Gendetails:
- N-acetylglucosamine-1-phosphate transferase; alpha and beta subunits
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human GNPTAB
- Molekulargewicht:
- 143kDa
- Proteindetails:
- N-acetylglucosamine-1-phosphotransferase subunits alpha/beta
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php