8ODP Antibody - middle region
Produktgrößen
25ul
£177,00
ARP49190-P050-25UL
100 ul
£412,00
ARP49190-P050-100UL
Über dieses Produkt
- SKU:
- ARP49190-P050
- Zusätzliche Namen:
- MTH1
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates; such as 8-oxo-dGTP; 8-oxo-dATP; 2-hydroxy-dATP; and 2-hydroxy rATP; to monophosphates; thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm; with some in the mitochondria; suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants; some of which encode distinct isoforms; have been identified. Additional variants have been observed; but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional; longer isoform (p26) has been described.
- Gendetails:
- nudix hydrolase 1
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of Human 8ODP
- Molekulargewicht:
- 21kDa
- Proteindetails:
- 7;8-dihydro-8-oxoguanine triphosphatase
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php