BATF2 Antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP47711-P050-25UL
100 ul
£412,00
ARP47711-P050-100UL
Über dieses Produkt
- SKU:
- ARP47711-P050
- Zusätzliche Namen:
- SARI
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- BATF2 is a AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection; it participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. It acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes (By similarity). It selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types; such as breast cancer; malignant glioma and metastatic melanoma. It possibly acts by interfering with AP-1 binding to CYR61 promoter.
- Gendetails:
- basic leucine zipper transcription factor; ATF-like 2
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human BATF2
- Molekulargewicht:
- 30kDa
- Proteindetails:
- Basic leucine zipper transcriptional factor ATF-like 2
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php