DCC antibody - middle region
Produktgrößen
25ul
£177,00
ARP46583-P050-25UL
100 ul
£412,00
ARP46583-P050-100UL
Über dieses Produkt
- SKU:
- ARP46583-P050
- Zusätzliche Namen:
- CRC18; CRCR1; MRMV1; HGPPS2; IGDCC1; NTN1R1
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules; and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK; also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts; and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor; and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.
- Gendetails:
- Deleted in colorectal carcinoma
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human DCC
- Molekulargewicht:
- 158kDa
- Proteindetails:
- Netrin receptor DCC
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php