CDH12 antibody - middle region
Produktgrößen
25ul
£177,00
ARP46400-P050-25UL
100 ul
£412,00
ARP46400-P050-100UL
Über dieses Produkt
- SKU:
- ARP46400-P050
- Zusätzliche Namen:
- CDHB
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- CDH12 belongs to the protocadherin protein family; a subfamily of the cadherin superfamily. It consists of an extracellular domain containing 6 cadherin repeats; a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain; a single membrane-spanning domain; and a small; highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development; perhaps specifically during synaptogenesis.
- Gendetails:
- Cadherin 12; type 2 (N-cadherin 2)
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human CDH12
- Molekulargewicht:
- 82kDa
- Proteindetails:
- Cadherin-12
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php