COL18A1 Antibody - Middle region
Produktgrößen
25ul
£177,00
ARP45877-P050-25UL
100 ul
£412,00
ARP45877-P050-100UL
Über dieses Produkt
- SKU:
- ARP45877-P050
- Zusätzliche Namen:
- KS; KNO; GLCC; KNO1
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins; extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin; a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities; so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants.
- Gendetails:
- collagen; type XVIII; alpha 1
- Host:
- Rabbit
- Immunogen:
- The immunogen for Anti-COL18A1 antibody is: synthetic peptide directed towards the Middle region of Human COIA1
- Molekulargewicht:
- 147 kDa
- Proteindetails:
- Collagen alpha-1(XVIII) chain
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php