DYRK1A antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP45797-P050-25UL
100 ul
£412,00
ARP45797-P050-100UL
Über dieses Produkt
- SKU:
- ARP45797-P050
- Zusätzliche Namen:
- MNB; DYRK; HP86; MNBH; MRD7; DYRK1
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence; a protein kinase domain; a leucine zipper motif; and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21; and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms.
- Gendetails:
- Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human DYRK1A
- Molekulargewicht:
- 85kDa
- Proteindetails:
- Dual specificity tyrosine-phosphorylation-regulated kinase 1A
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php