ESR1 antibody - middle region
Produktgrößen
25ul
£177,00
ARP45592-P050-25UL
100 ul
£412,00
ARP45592-P050-100UL
Über dieses Produkt
- SKU:
- ARP45592-P050
- Zusätzliche Namen:
- ER; ESR; Era; ESRA; ESTRR; NR3A1
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Hairy/enhancer of split-related proteins; such as HEY1; are basic helix-loop-helix (bHLH) transcription factors implicated in cell fate decision and boundary formation. HEY genes are direct transcriptional targets of the Notch signaling pathways in Drosophila and vertebrates. This gene encodes an estrogen receptor; a ligand-activated transcription factor composed of several domains important for hormone binding; DNA binding; and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function; but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer; endometrial cancer; and osteoporosis. Alternative splicing results in several transcript variants; which differ in their 5' UTRs and use different promoters.
- Gendetails:
- Estrogen receptor 1
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human ESR1
- Molekulargewicht:
- 66kDa
- Proteindetails:
- Estrogen receptor
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php