GALNT4 antibody - C-terminal region
Produktgrößen
25ul
£177,00
ARP45528-P050-25UL
100 ul
£412,00
ARP45528-P050-100UL
Über dieses Produkt
- SKU:
- ARP45528-P050
- Zusätzliche Namen:
- GALNACT4; GALNAC-T4
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- GALNT4 catalyzes the initial reaction in O-linked oligosaccharide biosynthesis; the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. It has a highest activity toward Muc7; EA2 and Muc2; with a lowest activity than GALNT2. This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain; a stem region; a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif; and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different; but overlapping; substrate specificities and patterns of expression. In vitro; the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon.
- Gendetails:
- UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C terminal region of human GALNT4
- Molekulargewicht:
- 67kDa
- Proteindetails:
- Polypeptide N-acetylgalactosaminyltransferase 4
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php