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Antikörper

FCER1A antibody - N-terminal region

Produktgrößen
25ul
£177,00
ARP45203-P050-25UL
100 ul
£412,00
ARP45203-P050-100UL
Über dieses Produkt
SKU:
ARP45203-P050
Zusätzliche Namen:
FCE1A; FcERI
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
The IgE receptor plays a central role in allergic disease; coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The allergic response occurs when 2 or more high-affinity IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes--potent effectors of the hypersensitivity response. The IgE receptor consists of 3 subunits: alpha; beta (MIM 147138); and gamma (MIM 147139); only the alpha subunit is glycosylated.
Gendetails:
Fc fragment of IgE; high affinity I; receptor for; alpha polypeptide
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human FCER1A
Molekulargewicht:
27kDa
Proteindetails:
High affinity immunoglobulin epsilon receptor subunit alpha
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody