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Antikörper

FOLH1 Antibody - middle region

Produktgrößen
25ul
£177,00
ARP44690-P050-25UL
100 ul
£412,00
ARP44690-P050-100UL
Über dieses Produkt
SKU:
ARP44690-P050
Zusätzliche Namen:
PSM; FGCP; FOLH; GCP2; PSMA; mGCP; GCPII; NAALAD1; NAALAdase
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates; including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate; central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates; resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region.
Gendetails:
folate hydrolase (prostate-specific membrane antigen) 1
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of Human FOLH1
Molekulargewicht:
48kDa
Proteindetails:
Glutamate carboxypeptidase 2
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody