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Antikörper

GHR antibody - N-terminal region

Produktgrößen
25ul
£177,00
ARP44230-P050-25UL
100 ul
£412,00
ARP44230-P050-100UL
Über dieses Produkt
SKU:
ARP44230-P050
Zusätzliche Namen:
GHBP; GHIP
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
GHR is a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene; called GHRd3; lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome; also known as the growth hormone insensitivity syndrome (GHIS); a disorder characterized by short stature.This gene encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene; called GHRd3; lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome; also known as the growth hormone insensitivity syndrome (GHIS); a disorder characterized by short stature. Other splice variants; including one encoding a soluble form of the protein (GHRtr); have been observed but have not been thoroughly characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gendetails:
Growth hormone receptor
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human GHR
Molekulargewicht:
70kDa
Proteindetails:
Growth hormone receptor
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody