Fbxo2 antibody - C-terminal region
Produktgrößen
25ul
£177,00
ARP43113-P050-25UL
100 ul
£412,00
ARP43113-P050-100UL
Über dieses Produkt
- SKU:
- ARP43113-P050
- Zusätzliche Namen:
- P; Fbs; FBG1; FBX2; Fbs1; Fbs2; NFB4; NFB42; Prpl4
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Fbxo2 is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins; preferentially those of the high-mannose type.
- Gendetails:
- F-box protein 2
- Host:
- Rabbit
- Molekulargewicht:
- 34kDa
- Proteindetails:
- F-box only protein 2
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php