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Antikörper

Anti-UBE2D1

Produktgrößen
25ul
£177,00
ARP43006-T100-25UL
100 ul
£373,00
ARP43006-T100-100UL
Über dieses Produkt
SKU:
ARP43006-T100
Zusätzliche Namen:
SFT; UBCH5; UBC4/5; UBCH5A; E2(17)KB1
Klonalität:
Polyclonal
Konzentration:
1.0 mg/ml
Weitere Details:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes; or E1s; ubiquitin-conjugating enzymes; or E2s; and ubiquitin-protein ligases; or E3s. UBE2D1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT); and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.
Gendetails:
Ubiquitin-conjugating enzyme E2D 1
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human UBE2D1
Molekulargewicht:
16kDa
Proteindetails:
Ubiquitin-conjugating enzyme E2 D1
Aufreinigung:
Protein A purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody