Dkk4 antibody - C-terminal region
Produktgrößen
25ul
£177,00
ARP42406-P050-25UL
100 ul
£412,00
ARP42406-P050-100UL
Über dieses Produkt
- SKU:
- ARP42406-P050
- Zusätzliche Namen:
- Dkk-4
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Dkk4 antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development; where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning; limb development; somitogenesis and eye formation. In the adult; Dkks are implicated in bone formation and bone disease; cancer and Alzheimer disease.
- Gendetails:
- Dickkopf homolog 4 (Xenopus laevis)
- Host:
- Rabbit
- Molekulargewicht:
- 24kDa
- Proteindetails:
- Dickkopf-related protein 4
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php