DMBT1 antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP42352-P050-25UL
100 ul
£412,00
ARP42352-P050-100UL
Über dieses Produkt
- SKU:
- ARP42352-P050
- Zusätzliche Namen:
- SAG; GP340; SALSA; muclin
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line. DMBT1 is expressed with transcripts of 6.0; 7.5; and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung; although the 7.5 kb transcript has not been characterized. The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor supressor gene; but rather play a role in the interaction of tumor cells and the immune system.
- Gendetails:
- Deleted in malignant brain tumors 1
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human DMBT1
- Molekulargewicht:
- 258kDa
- Proteindetails:
- Deleted in malignant brain tumors 1 protein
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php