ACTN4 antibody - C-terminal region
Produktgrößen
25ul
£177,00
ARP42203-P050-25UL
100 ul
£412,00
ARP42203-P050-100UL
Über dieses Produkt
- SKU:
- ARP42203-P050
- Zusätzliche Namen:
- FSGS; FSGS1; ACTININ-4
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- Alpha actinins belong to the spectrin superfamily which is a diverse group of cytoskeletal proteins; including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. ACTN4 is a nonmuscle; alpha actinin isoform which is concentrated in the cytoplasm; and thought to be involved in metastatic processes. Mutations in its gene have been associated with focal and segmental glomerulosclerosis.Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins; including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells; the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions; where it is involved in binding actin to the membrane. In contrast; skeletal; cardiac; and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies; where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle; alpha actinin isoform which is concentrated in the cytoplasm; and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.
- Gendetails:
- Actinin; alpha 4
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C terminal region of human ACTN4
- Molekulargewicht:
- 105kDa
- Proteindetails:
- Alpha-actinin-4
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php