DAB2 Antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP41937-P050-25UL
100 ul
£412,00
ARP41937-P050-100UL
Über dieses Produkt
- SKU:
- ARP41937-P050
- Zusätzliche Namen:
- DOC2; DOC-2
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells; but is down-regulated or absent from ovarian carcinoma cell lines; suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2; an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras); via its C-terminal proline-rich sequences; and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Gendetails:
- disabled homolog 2; mitogen-responsive phosphoprotein (Drosophila)
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human DAB2
- Molekulargewicht:
- 60kDa
- Proteindetails:
- Disabled homolog 2
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php