CYP2D6 antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP41675-T100-25UL
100 ul
£373,00
ARP41675-T100-100UL
Über dieses Produkt
- SKU:
- ARP41675-T100
- Zusätzliche Namen:
- CPD6; CYP2D; CYP2DL1; CYPIID6; P450C2D; P450DB1; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; P450-DB1
- Klonalität:
- Polyclonal
- Konzentration:
- 1.0 mg/ml
- Weitere Details:
- CYP2D6 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol; steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine; an adrenergic-blocking drug; sparteine and propafenone; both anti-arrythmic drugs; and amitryptiline; an anti-depressant.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol; steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine; an adrenergic-blocking drug; sparteine and propafenone; both anti-arrythmic drugs; and amitryptiline; an anti-depressant. The gene is highly polymorphic in the population; certain alleles result in the poor metabolizer phenotype; characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Gendetails:
- Cytochrome P450; family 2; subfamily D; polypeptide 6
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human CYP2D6
- Molekulargewicht:
- 55kDa
- Proteindetails:
- Cytochrome P450 2D6
- Aufreinigung:
- Protein A purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php