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Antikörper

CYP1A1 antibody - middle region

Produktgrößen
25ul
£177,00
ARP41404-P050-25UL
100 ul
£412,00
ARP41404-P050-100UL
Über dieses Produkt
SKU:
ARP41404-P050
Zusätzliche Namen:
AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
CYP1A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol; steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs); some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however; it is able to metabolize some PAHs to carcinogenic intermediates. CYP1A1 has been associated with lung cancer risk. This gene; CYP1A1; encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol; steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs); some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however; it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member; CYP1A2; is located approximately 25 kb away from CYP1A1 on chromosome 15. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gendetails:
Cytochrome P450; family 1; subfamily A; polypeptide 1
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human CYP1A1
Molekulargewicht:
58 kDa
Proteindetails:
Cytochrome P450 1A1
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody