DCX antibody - C-terminal region
Produktgrößen
25ul
£177,00
ARP41332-P050-25UL
100 ul
£412,00
ARP41332-P050-100UL
Über dieses Produkt
- SKU:
- ARP41332-P050
- Zusätzliche Namen:
- DC; DBCN; LISX; SCLH; XLIS
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- In the developing cortex; cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The protein contains two doublecortin domains; which bind microtubules. In addition; DCX interacts with LIS1; the regulatory gamma subunit of platelet activating factor acetylhydrolase; and this interaction is important to proper microtubule function in the developing cortex.In the developing cortex; cortical neurons must migrate over long distances to reach the site of their final differentiation. The protein encoded by this gene is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The encoded protein contains two doublecortin domains; which bind microtubules. In addition; the encoded protein interacts with LIS1; the regulatory gamma subunit of platelet activating factor acetylhydrolase; and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene are a cause of X-linked lissencephaly. Multiple transcript variants encoding at least three different isoforms have been found for this gene.
- Gendetails:
- Doublecortin
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C terminal region of human DCX
- Molekulargewicht:
- 49kDa
- Proteindetails:
- Neuronal migration protein doublecortin
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php