EXOSC6 antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP41087-T100-25UL
100 ul
£373,00
ARP41087-T100-100UL
Über dieses Produkt
- SKU:
- ARP41087-T100
- Zusätzliche Namen:
- p11; EAP4; MTR3; Mtr3p; hMtr3p
- Klonalität:
- Polyclonal
- Konzentration:
- 1.0 mg/ml
- Weitere Details:
- EXOSC6 constitutes one of the subunits of the multisubunit particle called exosome; which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known; however; it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs); but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own; but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs; thereby promoting their rapid degradation.This gene product constitutes one of the subunits of the multisubunit particle called exosome; which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known; however; it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs); but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own; but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs; thereby promoting their rapid degradation.
- Gendetails:
- Exosome component 6
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human EXOSC6
- Molekulargewicht:
- 30kDa
- Proteindetails:
- Exosome complex component MTR3
- Aufreinigung:
- Protein A purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php