ACO1 antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP40390-P050-25UL
100 ul
£412,00
ARP40390-P050-100UL
Über dieses Produkt
- SKU:
- ARP40390-P050
- Zusätzliche Namen:
- IRP1; ACONS; HEL60; IREB1; IREBP; IREBP1
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- ACO1; also known as iron regulatory element binding protein 1 (IREB1); is a cytosolic protein which binds to iron-responsive elements (IREs). It plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity; and hence grouped with the aconitase family of enzymes.Aconitase 1; also known as iron regulatory element binding protein 1 (IREB1); is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA; and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA; and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus; IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity; and hence grouped with the aconitase family of enzymes.
- Gendetails:
- Aconitase 1; soluble
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human ACO1
- Molekulargewicht:
- 98kDa
- Proteindetails:
- Cytoplasmic aconitate hydratase
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
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