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Antikörper

FBL antibody - N-terminal region

Produktgrößen
25ul
£177,00
ARP40366-T100-25UL
100 ul
£373,00
ARP40366-T100-100UL
Über dieses Produkt
SKU:
ARP40366-T100
Zusätzliche Namen:
FIB; FLRN; Nop1; RNU3IP1
Klonalität:
Polyclonal
Konzentration:
1.0 mg/ml
Weitere Details:
FBL is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3; U8; and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. FBL contains an N-terminal repetitive domain that is rich in glycine and arginine residues; like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3; U8; and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues; like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.
Gendetails:
Fibrillarin
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human FBL
Molekulargewicht:
35kDa
Proteindetails:
rRNA 2'-O-methyltransferase fibrillarin
Aufreinigung:
Protein A purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody