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Antikörper

ETS2 antibody - middle region

Produktgrößen
25ul
£177,00
ARP38592-P050-25UL
100 ul
£412,00
ARP38592-P050-100UL
Über dieses Produkt
SKU:
ARP38592-P050
Zusätzliche Namen:
ETS2IT1
Klonalität:
Polyclonal
Konzentration:
0.5 mg/ml
Weitere Details:
ETS2 contains an ETS DNA-binding domain and belongs to the ETS family. ETS2 is a target of protein kinase C and upregulates GM-CSF. Ets2 and its targets play essential roles in endothelial cell function. Coexpression of Ets-2 and SRC-1 significantly associated with the rate of recurrence and HER expression in breast cancer. Overexpression of ETS2 is associated with human esophageal squamous cell carcinoma. ETS transcriptions factors; such as ETS2; regulate numerous genes and are involved in stem cell development; cell senescence and death; and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al.; 2007 [PubMed 17986575]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gendetails:
V-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human ETS2
Molekulargewicht:
53kDa
Proteindetails:
Protein C-ets-2
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody