CHRNB2 antibody - middle region
Produktgrößen
25ul
£177,00
ARP37669-T100-25UL
100 ul
£373,00
ARP37669-T100-100UL
Über dieses Produkt
- SKU:
- ARP37669-T100
- Zusätzliche Namen:
- EFNL3; nAChRB2
- Klonalität:
- Polyclonal
- Konzentration:
- 1.0 mg/ml
- Weitere Details:
- Mutations in nAChRs are found in a rare form of nocturnal frontal lobe epilepsy . Previously; some nAChR mutations have been described that are associated with additional neurological features such as psychiatric disorders or cognitive defects. A new CHRNB2 mutation located in transmembrane region 3 (M3); outside the known ADNFLE mutation cluster. The CHRNB2 mutation I312M; which occurred de novo in twins; markedly increases the receptor's sensitivity to acetylcholine. Phenotypically; the mutation is associated not only with typical ADNFLE; but also with distinct deficits in memory. The cognitive problems are most obvious in tasks requiring the organization and storage of verbal information.
- Gendetails:
- Cholinergic receptor; nicotinic; beta 2 (neuronal)
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human CHRNB2
- Molekulargewicht:
- 57kDa
- Proteindetails:
- Neuronal acetylcholine receptor subunit beta-2
- Aufreinigung:
- Protein A purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php