CNOT8 Antibody - C-terminal region
Produktgrößen
25ul
£177,00
ARP35747-P050-25UL
100 ul
£412,00
ARP35747-P050-100UL
Über dieses Produkt
- SKU:
- ARP35747-P050
- Zusätzliche Namen:
- CAF1; POP2; CALIF; Caf1b; hCAF1
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- CNOT8 has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation; miRNA-mediated repression; translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. It associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.
- Gendetails:
- CCR4-NOT transcription complex; subunit 8
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CNOT8
- Molekulargewicht:
- 32kDa
- Proteindetails:
- CCR4-NOT transcription complex subunit 8
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php