CACNB4 antibody - C-terminal region
Produktgrößen
25ul
£177,00
ARP34959-P050-25UL
100 ul
£412,00
ARP34959-P050-100UL
Über dieses Produkt
- SKU:
- ARP34959-P050
- Zusätzliche Namen:
- EA5; EJM; CAB4; EIG9; EJM4; EJM6; CACNLB4
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- CACNB4 is a member of the beta subunit family; a protein in the voltage-dependent calcium channel complex. CACNB4 plays an important role in calcium channel function by modulating G protein inhibition; increasing peak calcium current; controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. This gene encodes a member of the beta subunit family; a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1; alpha-2/delta; beta; and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist; either expressed from similar genes or the result of alternative splicing. The protein described in this record plays an important role in calcium channel function by modulating G protein inhibition; increasing peak calcium current; controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Alternate transcriptional splice variants of this gene; encoding different isoforms; have been characterized.
- Gendetails:
- Calcium channel; voltage-dependent; beta 4 subunit
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C terminal region of human CACNB4
- Molekulargewicht:
- 55kDa
- Proteindetails:
- Voltage-dependent L-type calcium channel subunit beta-4
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php