DMTF1 antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP34603-P050-25UL
100 ul
£412,00
ARP34603-P050-100UL
Über dieses Produkt
- SKU:
- ARP34603-P050
- Zusätzliche Namen:
- DMP1; DMTF; MRUL; hDMP1
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- This gene encodes a transcription factor that contains a cyclin D-binding domain; three central Myb-like repeats; and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40% of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
- Gendetails:
- cyclin D binding myb like transcription factor 1
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human DMTF1
- Molekulargewicht:
- 84kDa
- Proteindetails:
- cyclin-D-binding Myb-like transcription factor 1
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php