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Antikörper

DMAP1 antibody - N-terminal region

Produktgrößen
25ul
£177,00
ARP32917-T100-25UL
100 ul
£373,00
ARP32917-T100-100UL
Über dieses Produkt
SKU:
ARP32917-T100
Zusätzliche Namen:
EAF2; SWC4; MEAF2; DNMAP1; DNMTAP1
Klonalität:
Polyclonal
Konzentration:
1.0 mg/ml
Weitere Details:
DMAP1 is a subunit of several; distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase; histone deacetylase 2 is added to this complex; providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6; among others. Alternatively spliced transcript variants encoding the same protein have been described.
Gendetails:
DNA methyltransferase 1 associated protein 1
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human DMAP1
Molekulargewicht:
51kDa
Proteindetails:
DNA methyltransferase 1-associated protein 1
Aufreinigung:
Protein A purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody