GFI1 antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP32557-P050-25UL
100 ul
£412,00
ARP32557-P050-100UL
Über dieses Produkt
- SKU:
- ARP32557-P050
- Zusätzliche Namen:
- SCN2; GFI-1; GFI1A; ZNF163
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- GFI1 may be a transcription factor involved in regulating the expression of genes active in the S phase during cell cycle progression in T-cells. GFI1 may be involved in tumor progression. Defects in GFI1 are a cause of autosomal dominant severe congenital neutropenia (SCN) and dominant nonimmune chronic idiopathic neutropenia of adults (NI-CINA) This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts; including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia; and also dominant nonimmune chronic idiopathic neutropenia of adults; which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants; encoding the same protein; have been identified for this gene.
- Gendetails:
- Growth factor independent 1 transcription repressor
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human GFI1
- Molekulargewicht:
- 45kDa
- Proteindetails:
- Zinc finger protein Gfi-1
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php