ELF3 antibody - middle region
Produktgrößen
25ul
£177,00
ARP32247-T100-25UL
100 ul
£373,00
ARP32247-T100-100UL
Über dieses Produkt
- SKU:
- ARP32247-T100
- Zusätzliche Namen:
- ERT; ESX; EPR-1; ESE-1
- Klonalität:
- Polyclonal
- Konzentration:
- 1.0 mg/ml
- Weitere Details:
- ELF3 is a novel; highly tissue-restricted member of the ets transcription factor/oncogene family. ELF3 contains two putative DNA binding domains: an ETS domain; which is unique in that the 5' half shows relatively weak homology to known ets factors; and an A/T hook domain; found in HMG proteins and various other nuclear factors. In contrast to any known ets factors; ELF3 is expressed exclusively in epithelial cells. ELF3 is expected to be a critical regulator of epithelial cell differentiation. ETS factor ELF3 is a transcriptional regulator of angiopoietin-1 gene regulation in the setting of inflammation. ELF3 overexpressed early during human breast tumorigenesis. ELF3 expression confers a transformed and in vitro metastatic phenotype to otherwise normal MCF-12A cells. ELF3 mediates the expression of TGF-beta RII; and the transcriptional inhibition of ets-related transcription factor could be a one of the mechanisms of colonic carcinogenesis. ELF3 is positively and negatively modulated by other interacting proteins including Ku70; Ku86; p300; and CBP.
- Gendetails:
- E74-like factor 3 (ets domain transcription factor; epithelial-specific )
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human ELF3
- Molekulargewicht:
- 41kDa
- Proteindetails:
- ETS-related transcription factor Elf-3
- Aufreinigung:
- Protein A purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php