GRM6 antibody - middle region
Produktgrößen
25ul
£177,00
ARP31907-P050-25UL
100 ul
£412,00
ARP31907-P050-100UL
Über dieses Produkt
- SKU:
- ARP31907-P050
- Zusätzliche Namen:
- mGlu6; CSNB1B; GPRC1F; MGLUR6
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- GRM6 is the receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity.L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors; that have been divided into 3 groups on the basis of sequence homology; putative signal transduction mechanisms; and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4; GRM6; GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
- Gendetails:
- Glutamate receptor; metabotropic 6
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human GRM6
- Molekulargewicht:
- 95kDa
- Proteindetails:
- Metabotropic glutamate receptor 6
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php