EAP30 antibody - N-terminal region
Produktgrößen
25ul
£177,00
ARP31531-P050-25UL
100 ul
£412,00
ARP31531-P050-100UL
Über dieses Produkt
- SKU:
- ARP31531-P050
- Zusätzliche Namen:
- Dot3; EAP30; VPS22
- Klonalität:
- Polyclonal
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia (AML). In addition to its elongation activity; ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.SNF8; VPS25 (MIM 610907); and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II); a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8; VPS25; and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL; MIM 600284) (Slagsvold et al.; 2005 [PubMed 15755741]; Kamura et al.; 2001 [PubMed 11278625]).[supplied by OMIM].
- Gendetails:
- SNF8; ESCRT-II complex subunit; homolog (S. cerevisiae)
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human EAP30
- Molekulargewicht:
- 29kDa
- Proteindetails:
- Vacuolar-sorting protein SNF8
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php